determination of cut off level for screening titer of Antinuclear Antibody-Hep-2 Test (ANA)
نویسندگان
چکیده
منابع مشابه
Second generation analysis of antinuclear antibody (ANA) by combination of screening and confirmatory testing.
BACKGROUND For the serological diagnosis of systemic autoimmune rheumatic diseases, a two-tier approach starting with sensitive antinuclear antibody (ANA) detection by indirect immunofluorescence (IIF) on HEp-2 cells followed by characterization of positive findings with different immunoassays is recommended. To overcome drawbacks of this approach, we developed a novel technique allowing the co...
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1. Gandhi MK, Khanna R. Human cytomegalovirus: clinical aspects, immune regulation, and emerging treatments. Lancet Infect Dis. 2004;4:725-738. 2. Hislop AD, Taylor GS, Sauce D, Rickinson AB. Cellular responses to viral infection in humans: lessons from Epstein-Barr virus. Annu Rev Immunol. 2007;25: 587-617. 3. Gandhi MK, Wills MR, Okecha G, et al. Late diversification in the clonal composition...
متن کاملSTUDY OF NUCLEAR LEVEL DENSITY AND SPIN CUT-OFF FACTORS
Nuclear level densities and spin cut-off factors have been deduced for nuclei in the mass region 24‹A‹63,from a microscopic theory, which includes nuclear pairing interaction. Single particle levels for both Seeger and Nilsson potentials were used in the calcdations. Level densities extracted from the theory are compared with their conesponding experimental values, It is found that the overall...
متن کاملScreening for IgG antinuclear autoantibodies by HEp-2 indirect fluorescent antibody assays and the need for standardization.
We evaluated 5 commercially available HEp-2 antinuclear antibody (ANA) indirect fluorescent antibody (IFA) assays using patient serum samples from 45 patients with rheumatoid arthritis, 50 with systemic lupus erythematosus (SLE), 35 with scleroderma, 20 with Sjögren syndrome, 10 with polymyositis, and 100 healthy control subjects. In addition, 12 defined serum samples from the Centers for Disea...
متن کاملELISA Cut-off Point for the Diagnosis of Human Brucellosis; a Comparison with Serum Agglutination Test
Background: Brucellosis is a world-wide disease, which has a diverse clinical manifestation, and its diagnosis has to be proven by laboratory data. Serum agglutination test (SAT) is the most-widely used test for diagnosing brucellosis. The enzyme linked immunosorbent assay (ELISA) can also determine specific antibody classes against brucella. It is a sensitive, simple and rapid test, which coul...
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ژورنال
عنوان ژورنال: Turkish Bulletin of Hygiene and Experimental Biology
سال: 2017
ISSN: 0377-9777,1308-2523
DOI: 10.5505/turkhijyen.2016.27870